Graduate Seminar - Glycomaterials for the treatment of severe and penetrating traumatic brain injuries
Dr. Lohitash Karumbaiah is Associate Professor in the Department of Animal & Dairy Science at UGA. Dr. Karumbaiah's research interests center around carbohydrates. Carbohydrates are an important and often under appreciated class of biological macromolecules that play important roles in development, and in repair and regeneration post-injury. Defects in carbohydrate biosynthesis and alterations in carbohydrate composition are known to result in several undesirable outcomes such as developmental abnormalities, cartilage breakdown and reduced myocardial tissue integrity to name a few. Carbohydrates also play important roles in a number of biological processes, a few of which include: binding trophic factors and cytokines, controlling stem cell differentiation, cell fate and self-renewal, directing neuronal path-finding, and protecting and stabilizing proteins. While bio-compatible synthetic polymer and peptide based biomaterials have gained widespread acceptance for regenerative medicine applications, the potential of natural carbohydrate based biomaterials for regenerative medicine has not been fully explored. My research integrates methodologies from engineering disciplines and biology, and uses an interdisciplinary approach to help understand, manipulate and design novel carbohydrate based biomaterials for spinal cord injuries (SCI), traumatic brain injuries (TBI) and neural interfacing applications.
Seminar will take place 11:30am - 12:20pm in Dawson Hall Room 310.