Hea Jin Park

Education

Research

My research focuses on defining the beneficial role of bioactive food compounds and functional foods in human health and on investigating their mechanisms of action in chronic diseases and perinatal development. For more information, see the Bioactive Compounds and Health Laboratory.

Teaching

Human Nutrition and Food, Honors (FDNS2100H)

Cultural Aspects of Foods and Nutrition (FDNS4630/6630)

Nutrition and Disease Processes II (FDNS8550)

Journal Articles

1. ES Waters, EE Kaiser, X Yang, MM Fagan, KM Scheulin, J Jeon, SK Shin¸ HA Kinder, A Kumar, SR Platt, KJ Duberstein, HJ Park, J Xie, FD West. Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke. IBRO reports, In press, 2021
2. Jeon, J Lourenco, EE Kaiser, ES Waters, KM Scheulin, X Fang, HA Kinder, SR Platt, MJ Rothrock Jr, TR Callaway, FD West, HJ Park. Dynamic changes in the gut microbiome at the acute stage of ischemic stroke in a pig model. Frontiers in Neuroscience, 3;14:587986, 2020
3. X Fang, W Sun, J Jeon, M Azain, H Kinder, J Ahn, HC Chung, Q Zhao, S Rayalam,  HJ Park. Perinatal docosahexaenoic acid supplementation improves cognition and alters brain functional organization in piglets. Nutrients, 15; 12(7): E2090, 2020
4. EE Kaiser, ES Waters, MM Fagan, KM Scheulin, SR Platt, J Jeon, X Fang, HA Kinder, SK Shin, KJ Duberstein, HJ Park, FD West. Characterization of tissue and functional deficits in a clinically translatable pig model of acute ischemic stroke. Brain Research, 1;1736:146778, 2020
5. Fang, M Azain, K Crowe-white, JL Mumaw, JA Grimes, C Schimdt, M Barletta, S Rayalam, HJ Park. Effect of acute ingestion of green tea extract and lemon juice on oxidative stress and lipid profile in pigs fed high-fat diet. Antioxidants (Basel), 23;8(6): 195, 2019
6. X Fang, J Chung, E Olsen, Snider I, Earls RH, JH Jeon, HJ Park, JK Lee. Depletion of Regulator-of-G-protein signaling-10 in mice exaggerates high-fat diet-induced insulin resistance and inflammation, and this effect is mitigated by dietary green tea extract. Nutrition Research, 70: 50-59, 2019
7. G Simchick, A Shen, B Campbell, HJ Park, FD West, Q Zhao. Pig brains have homologous resting state networks to human brains. Brain Connectivity, 9(7): 566-579, 2019
8. AK Knight, HJ Park,DB Hausman, J Fleming, V Andersen, G Rosa, M Caudill, O Malysheva, GPA Kauwell, A Sokolow, S Fisher, AK Smith, LB Bailey. Association between one-carbon metabolism indices and DNA methylation status in maternal and cord blood. Scientific Reports, 15 ;8(1):16873, 2018
9. RA Reed, M Barletta, JA Grimes, JL Mumaw, HJ Park, X Fang#, M Azain, S Giguere, and JE Quandt. Accuracy of an oscillometric blood pressure monitor in anesthetized pigs. Laboratory Animals. 52(5):490-496, 2018
10. NM Hohos, AK Smith, HJ Park, DB Hausman, LB Bailey, DC Shade, RB Meagher. CD4+ and CD8+ T cell-specific DNA cytosine methylation differences associated with obesity. Obesity (Silver Spring), 26(8): 1312-1321, 2018
11. Park HJ, Bailey LB, Shade DC, Hausman DB, Hohos NM, Meagher RB, Kauwell GP, Lewis RD, Smith AK. Distinctions in gene-specific changes in DNA methylation in response to folic acid supplementation between women with normal weight and obesity. Obesity Resesrach and Clinical Practice. 11(6): 665-676, 2017.
12. DC Shade, HJ Park*, DB Hausman, Hohos NM, RB Meagher, GPA Kauwell, V Kilaru, RD Lewis, AK Smith, LB Bailey. DNA Methylation Changes in Whole Blood and CD16+ Neutrophils in Response to Chronic Folic Acid Supplementation in Women of Childbearing Age. International Journal for Vitamin and Nutrition Research. 87 (5-6):271-278, 2017
13. JD Gordon, DB Hausman, LB Bailey, RD Lewis, EM Laing, HJ Park. Impact of gluten-containing foods on folate intake of women of childbearing age. The Digest, Research Dietetics Practice Group's newsletter, 51(1): 2-7, 2016
14. MY Chung, E Mah, C Masterjohn, SK Noh, HJ Park, RM Clark, YK Park, JY Lee, RS Bruno. Green Tea Lowers Hepatic COX-2 and prostaglandin E2 in rats with dietary fat-induced nonalcoholic steatohepatitis. Journal of Medicinal Food, 18(6) : 648-55, 2015
15. E Mah, SK Noh, KD Ballard, HJ Park, JS Volek, RS Bruno. Supplementation of a γ-tocopherol-rich mixture of tocopherols in healthy men protects against vascular endothelial dysfunction induced by postprandial hyperglycemia. Journal of Nutritional Biochemistry 24(1):196-203, 2013
16. HJ Park, JY Lee, MY Chung, YK Park, AM Bower, SI Koo, C Giardina, RS Bruno. Green tea extract suppresses NFκB activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis. Journal of Nutrition. 142(1):57-63. 2012
17. MY Chung, HJ Park, JE Manautou, SI Koo, RS Bruno. Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by pro-inflammatory enzymes. Journal of Nutritional Biochemistry. 23(4):361-7. 2012
18. JM Bustamante, HJ Park, RL Tarleton. Report of the 2nd Chagas Drug Discovery Consortium meeting, held on 3 November 2010; Atlanta GA, USA. Expert Opinion on Drug Discovery. 6(9):965-73. 2011
19. Y Yang, JM Seo, A Nguyen, TX Pham, HJ Park, Y Park, B Kim, RS Bruno, J Lee. Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice. Journal of Nutrition. 141(9):1611-7. 2011
20. DC Montrose, NA Horelik, JP Madigan, GD Stoner, L Wang, RS Bruno, HJ Park, C Giardina, DW Rosenberg. Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis, 32(3):343-50. 2011
21. HJ Park, DD DiNatale, M-Y Chung, Y-K Park, J-Y Lee, SI Koo, M O’Connor, JE Manautou, RS Bruno. Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhances hepatic antioxidant defenses in ob/ob mice. Journal of Nutritional Biochemistry, 22(4):393-400, 2011
22. MY Chung, SF Yeung, HJ Park, JS Volek, RS Bruno. Dietary α- and γ-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and inflammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis. Journal of Nutritional Biochemistry, 21(12): 1200-6, 2010
23. HJ Park, E Mah, RS Bruno. Validation of high-performance liquid chromatography-boron-doped diamond detection for assessing hepatic glutathione redox status. Analytical Biochemistry, 15: 407(2): 151-9, 2010
24. HJ Park, RS Bruno. Hepatoprotective activities of green tea in nonalcoholic fatty liver disease. AGRO FOOD INDUSTRY HI-TECH, 21(n1): 37-40, 2010
25. HJ Park, SR Davis, HY Liang, DW Rosenberg, RS Bruno. Chlorogenic acid differentially alters hepatic and small intestinal thiol redox status without protecting against Azoxymethane-induced colon carcinogenesis in mice. Nutrition and Cancer, 62(3): 362-70, 2010